The Pattern Electroretinogram in Optic Nerve Demyelination
نویسندگان
چکیده
منابع مشابه
The Optic Nerve: “tip of the Iceberg” of Demyelination
Multi ple sclerosis (MS) and neuromyeliti s opti ca (NMO) are disti nct immune-mediated infl ammatory conditi ons that characteristi cally att ack the opti c nerve, brain and spinal cord. Associated opti c nerve demyelinati on and axonal loss lead to a range of visual complaints and disabiliti es that may be the presenti ng symptoms of these disorders. Physiological and anatomical measures, inc...
متن کاملProtection of Pattern Electroretinogram and Retinal Ganglion Cells by Oncostatin M after Optic Nerve Injury
Injury to retinal ganglion cell (RGC) axons leads to selective loss of RGCs and vision. Previous studies have shown that exogenous neurotrophic factors promote RGC survival. We investigated the neuroprotective effects of oncostatin M (OSM), a member of the IL-6 family of cytokines, on pattern electroretinogram (PERG) and RGC survival after optic nerve crush (ON-crush) in the mouse. BALB/C mice ...
متن کاملOptic nerve head component responses of the multifocal electroretinogram in MS.
OBJECTIVE To employ a novel stimulation paradigm in order to elicit multifocal electroretinography (mfERG)-induced optic nerve head component (ONHC) responses, believed to be contingent upon the transformation in electrical transmission properties of retinal ganglion cell axons from membrane to saltatory conduction mechanisms, as they traverse the lamina cribrosa and obtain oligodendrocyte myel...
متن کاملNeurophysiological investigation in optic nerve disease: combined assessment of the visual evoked response and electroretinogram.
The electroretinogram (ERG) and the pattern visual evoked responses (VER) obtained from patients with suspected primary optic nerve lesions have been analysed. Patients with hereditary optic atrophy or optic nerve lesions with retinal disease or with systemic disorders were excluded from the analysis. According to the results of the ERG functions and VER, 83 patients with suspected primary opti...
متن کاملThe optic nerve head component of the monkey's (Macaca mulatta) multifocal electroretinogram (mERG)
To search for an optic nerve head component (ONHC) in the monkey's (Macaca mulatta) multifocal electroretinogram (mERG), mERGs from three animals were recorded with different electrode configurations. A component with a latency that varied with distance from the optic nerve head was easily identified by eye in recordings from the speculum of a Burian-Allen electrode referenced to a DTL on the u...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 1983
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s031716710004511x